2,4-Diamino-5-deaza-6-substituted pteridines as antitubercular agents.
Reynolds RC; Seitz, L.; Pathak, V.; Barrow, W.; Ross, L. J.; White, E.L.; Suling, W.
J. Med.Chem. 2005.
2-Alkoxycarbonylaminopyridines: inhibitors of Mycobacterium tuberculosis FtsZ.
White, E.L.; Suling, W.J.; Ross, L.J.; Seitz, L.E.; Reynolds, R.C.
J. Antimicrob. Chemother. 2002; Jul;50(1):111-4.
A Cell-based Luminescence Assay is Effective for High-throughput Screening of Potential Influenza Antivirals.
Noah JW: Severson W: Noah DL; Rasmussen L; White EL; Jonsson CB.
Antiviral Res. 2006; In press.
A cell based luminescence assay is effective for high throughput screening of potential influenza antivirals.
Noah, J., Severson, W., Noah, D. Rasmussen, L., White, E. L. and C. B. Jonsson.
Antiviral Res. 2006; Accepted.
A comprehensive genetic analysis of mouse inbred strains.
Tsang, S., Sun, Z., Luke, B.T., Stewart, C., Shen, H., Suzuki, T., Rasmussen, L., Copeland, N.G., and D. J. Munroe.
Genomics. 2004 (Submitted for publication)
A Facile Method for Deprotection of Trityl Ethers Using Column Chromatography.
Pathak, A.K.; Pathak, V.; Seitz, L.E.; Tiwari, K.N.; Akhtar, M.S.; Reynolds, R.C.
Tetrahedron Letters 2001; 42(44), 7755-7757.
A longitudinal study of Bayou virus, hosts and habitat.
McIntyre, N., Chu, Y.K., Owen, R., Abuzeineh, A., De la Sancha, N., Dick, C., Holsomback, T., Nisbett, R., Jonsson, C.B.
Amer. J. Trop. Med. Hyg. 2005; Amer. J. Trop. Med. Hyg. 73:1043-1049.
A New 2-Carbamoyl Pteridine that Inhibits Mycobacterial FtsZ.
Reynolds, R.C.; Srivastava, S.; Ross, L.J.; Suling, W.J.; E.L. White.
Bioorg. Med. Chem. Lett. 2004; 14: 3161-4.
A Novel Inhibitor of Mycobacterium tuberculosis Pantothenate Synthetase.
White, E.L.; Southworth, K.; Ross, L.; Cooley, S.; Gill, R.B.; Sosa, M.I.; Manouvakhova, A.; Rasmussen, L.; Goulding, C.; Eisenberg, D.; Fletcher T.M. III.
J. Biomol. Screening. 2006; In press.
A secondary element in the Geminivirus replication domain interacts with the origin of replication of Geminiviruses.
Severson, W. E. and S. Hanson.
Manuscript in preparation 2005.
Activation of Chloride Secretion in Cystic Fibrosis and Tissues by the Substituted Imidazole SRI 2931.
Jones, J. R.; Schwiebert, E. M.; DuVall, M. D.; Venglarik, C. J.; Wen, H.; Kovacs, T.; Mazur, M.; Clancy, J. P.; Braunstein, G.; Bates, E.; Greer, H.; Maddry, J. A.; Sorscher, E. J.
Biochemistry 2003; 42, 13241-9.
Activators of Viral Gene Expression in Polarized Epithelial Monolayers Identified by Rapid-Throughput Drug Screening.
Sorscher, E. S.; Harris, J.; Alexander, M.; Rottgers, A.; Hardy, K.; Ponnazhagen, S.; McClintock, J.; Webster, A.; Maddry, J.; Hong, J. S.
Gene Therapy 2005; (accepted for publication).
Altered Immunomodulating and Toxicological Properties of Degraded Quillaja saponaria Molina Saponins.
Marciani, D.J.; Pathak, A.K.; Reynolds, R.C.; Seitz, L.S.; May, R.D.
International Immunopharmacology 2001; Vol 1/4, 813-818.
Analysis of biomarkers of response to FB642 in human neuroblastoma cells in vitro.
Izbicka, E., Carrizales,. G., Rani, S., and G. Piazza.
European Journal of Cancer 2002; 38: S38.
Analysis of K-ras codon 12 mutations in colorectal cancer.
Pike, K.M., Plona, T.M., Medjahed, D., Kleif, S., Rasmussen, L., Stewart, C., and David J. Munroe.
Journal of the National Cancer Institute. 2004; (Submitted for publication).
Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis.
Xu, Z-Q., Barrow, W.W., Suling, W.J., Westbrook, L., Barrow, E., Lin, Y-M., Flavin, M.T.
Bioorg. Med. Chem. 2004; 12:1199-1207.
Antimicrobial activity of 2-methyladenosine.
Barrow, E.W., Westbrook, L., Bansal, N., Suling, W.J., Maddry, J.A., Parker, W.B., Barrow, W.W.
J. Antimicrob. Chemother. 2003; 52:801-808.
Antimycobacterial activity of 1-deaza-7, 8-dihydropteridine derivatives against Mycobacterium tuberculosis and Mycobacterium avium complex. Suling, W.J. and Maddry, J.A.
J. Antimicrob. Chemother. 2001; 47:451-454.
Antimycobacterial Activity of 2-Methyladenosine.
Barrow, E. W.; Westbrook, L.; Bansal, N.; Suling, W. J.; Maddry, J. A.; Parker, W. B.; Barrow, W. W.
J. Antimicrob. Chemother. 2003; 52, 801-8.
Antimycobacterial agents: Part-I. Thio-analogs of purine.
Pathak, A.K.; Pathak, V.; Seitz, L.E.; Suling, W.J.; Reynolds, R.C.
J. Med. Chem. 2004; 47(1), 273-6.
Antitumor in vitro activity of an inhibitor of EGFR tyrosine kinase against colony formation of freshly explanted human tumor cells in the human tumor cloning assay.
DeBona, J., Rowinsky, E., Takimoto, C., Piazza, G., and Medina, L.
Proc. Amer. Ass. Cancer Res. 2002; 43: 786.
Antiviral activity of ribavirin against Hantaan virus correlates with production of ribavirin-5’-triphosphate, not with inhibition of inosine monophosphate dehydrogenase.
Sun, Y., Chung D., Chu, Y.K., Jonsson, C.B. and W.B. Parker.
Antimicrobial Agents and Chemotherapy. 2006; Accepted.
Arabinofuranose disaccharide analogs as inhibitors of Mycobacterium tuberculosis.
Pathak, A.K., Pathak, V., Kulshrestha, M., Kinnaird, D., Suling, W.J., Gurcha, S.S., Besra, G.S., Reynolds, R.C.
Tetrahedron 2003; 59:10239-10248.
Astrocyes refill intracellular Ca2+ stores without cytplasmic Ca2+ elevation: a funcional rather than a structural ability.
Grimaldi M. et al.
2005; (Submitted).
Biochemical and genetic characterization of the metabolism of 2-methyl-adenosine in Mycobacterium smegmatis.
Chen, C-K., Barrow, E.W., Allan, P.W., Bansal, N., Maddry, J.A., Suling, W.J., Barrow, W.W., Parker, W.B.
Microbiology, 2002; 148:289-295.
Biochemistry of Mycobacterium tuberculosis FtsZ.
White, E.L.; Ross, L.J.; Reynolds, R.C.
Instituto Juan March de Estudios e Investigaciones. 2002; 146, 23-5.
Biomarkers of in vitro response to HMN-176 in human ovarian cell lines.
Izbicka, E., Carrizales, G., Kadapakkam, S., Scott, C., Piazza, G., Salunek, M., and R. Getts.
European Journal of Cancer, 2002; 38: S40.
Biomarkers of in vivo response to bcl-2 antisense in human prostate xenografts.
Izbicka, E., Beckendorf, B., Chavez, J., Getts, R., Piazza, G., Wynne, H., and Tolcher, A.
European Journal of Cancer, 2002; 38: S145.
Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer.
Rose JD, Parker WB, Secrist JA III
Nucleosides, Nucleotides, and Nucleic Acids. 2005; 24: 809-813.
Boat conformations synthesis, NMR spectroscopy, and molecular dynamics of methyl 4,6-O-benzylidene-3-deoxy-3-phthalimido-alpha-D-altropyranoside derivatives.
Coxon B, Reynolds R.C.
Carbohydrate Research 2001; 331(4), 461-7.
Breadth of anti-tumor activity of CK0238273, a novel inhibitor of mitotic kinesin KSP.
Gonzales, P., Boehme, M., Bienek, A., Piazza, G. et al.,
Proc. Amer. Ass. Cancer Res. 2002; 43: 269.
Cannabinoids and elevated cAMP protect against glutamate neurotoxicity.
European Hampson A. and Grimaldi M. J. Neuroscience 2001; 13(8):1229-1236.
cis-Acting signals in encapsidation of Hantaan virus S-segment viral genomic RNA by its N protein. Severson, W.E., Xu, X. and C.B. Jonsson.
J. Virol. 2001; 75:2646-2652.
Cloning, expression and characterization of Mycobacterium tuberculosis dihydrofolate reductase.
White, L. E., Ross, L. J., Cunningham, A., Escuyer, V.
FEMS. Microbiol. Lett. 2004; 232: 101-105.
Combinatorial chemoprevention: efficacy of lovastatin and exisulind on the formation and progression of aberrant crypt foci.
Kim, K. P., Whitehead, C. Piazza, G. and Wargovich, M. J.
Anticancer Res. 2004; 24: 1805-1811.
Common sites of retroviral integration in mouse hematopoietic tumors identified by high-throughput, SNP-based, mapping.
Shen, H., Suzuki, T., Munroe, D.J., Stewart, C., Rasmussen, L., Gilbert, D.J., Jenkins, N.A., and N.G. Copeland.
Journal of Virology 2003; 77: 1584-1588.
Copper catalyzed arylation with boronic acids for the synthesis of N1-aryl purine nucleosides.
Strouse, J.J., Jeselnik, M., Tapaha, F., Jonsson, C.B., Parker, W.B., Arterburn, J.A.
Tetrahedron Letters 2005; 46:5699-5702.
Critical Role of Egrl in Hippocampal Synaptic Enhancement Induced by Tetanic Stimulation and Amputation. Wei, F.; Xu, Z.; Qu, Z.; Milbrandt, J.; Zhuo, M. J. Cell Biol. 2001; 149, 1325-1334.
Cross-linking Yields Better Picture of Intron.
Noah, J.W. Chemical Engineering and News 2003; 81(45) 44. Abstract and Review.
Degradation of Quillaja Saponaria Molina saponins: Loss of the protective Effects of a herpes simplex virus 1 sub-unit vaccine.
Marciani, D.J.; Ptak, R.G.; Voss, T.G.; Reynolds, R.C.; Pathak, A.K.; Chamblin, T.L.; Scholl D.R.; May, R.D. International Immunopharmacology 2002; 2(12), 1703-11.
Development and application of an HTS assay for HIV-1 integrase enzyme activities. John, S., Fletcher III, T., and CB Jonsson.
J. Biomol. Scr. 2005; J. Biomol. Scr.10:606-614.
Development and Validation of a High Throughput Screen for Inhibitors of SARS CoV and Its Application in Screening of a 100,000 Compound Library.
Severson, W.E.; Shindo, N.; Sosa, M.; Fletcher, T. III; White, E.L.; Ananthan, S.; Jonsson, C.B.
J. Biomol. Screening. 2006; In press.
Development, validation and optimization of a luminescence-based high throughput screen for inhibitors of Severe Acute Respiratory Syndrome.
Severson, W.E., Shindo, N., Sosa, M., Fletcher, T., White, L. and C. Jonsson.
J. Biomol. Scr. 2006; Accepted.
Differential growth inhibitory and apoptosis inducing activity of COX-2 selective inhibitors, celecoxib and rofecoxib, in human breast and prostate tumor cell lines: evidence for a COX-2 independent mechanism of action.
Piazza, G., Estlack, L., Revilla, M., Cerno, C., Carrizales, G., Agyin, J., Izbicka, E., and J. Quada.
Proc. Amer. Ass. Cancer Res. 2003.
Differential multimerization of Moloney murine leukemia virus integrase purified under non-denaturing conditions.
Villanueva, R.A, Jonsson, C. B., Jones, J., Georgiadis, M.M. and M. J. Roth.
Virol. 2003; 316:146-60.
Docking and Biological Activity of Pteridine Analogs: Search for Inhibitors of Pteridine Reductase Enzymes from Trypanosoma cruzi. Schormann, N.; Senkovich, O.; Ananthan, S.; Chattopadhyay, D. J. Mol. Struct. 2003; 633, 37-44.
E. Transcriptional Control of Intestinal CYP3A4 by 1γ
,25-Dihydroxy Vitamin D3.
Thummel K. E., Brimer, C. Yasuda, K., Thottassery, J., Senn, T., Lin, Y., Ishizuka, H., Kharasch, E., Schuetz, J., and Schuetz.
Molecular Pharmacology 2001; 60:1399-1406.
Effects of maturase binding and Mg2+ concentration on group II intron RNA folding investigated by UV cross-linking.
Noah, J.W., and Lambowitz, A.M.
Biochemistry 2003; 42(44) 12466-80.
Efficacy of exisulind and docexel combination in an orthotopic human NSCLC rat model involves apoptosis induction and angiogenesis inhibition.
Whitehead, C. M., Earle, K. A., Xu, S., Chan, D., Zhao, T. L., Alila, H., Pamukcu, R., Klein-Szanto, A., Bunn, P., Thompson, W. J., and G. A. Piazza.
Proc. Amer. Ass. Cancer Res. 2001; 43.
Emerging therapeutic targets in tuberculosis: post-genomic era.
Khasnobis, S., Escuyer, V.E. and Chatterjee, D.
Expert Opin. Ther. Targets. 2002; 6: 21-40.
Enhancement of nucleoside cytotoxicity through nucleotide prodrugs.
Rose JD, Parker WB, Someya H, Shaddix SC, Montgomery JA, and Secrist JA III.
J. Med. Chem. 2002; 45: 4505-4512.
Essential amino acids of the Hantaan virus N protein in its interaction with RNA.
Severson, W.E., Xu, X., Kuhn, M., Senutovitch, N., Thokala, M., Ferron, F., Longhi, S., Canard, B. and C.B. Jonsson.
J. Virol. 2005; 79:10032-10039.
Essential amino acids of the Hantaan virus N protein in its interaction with vRNA.
Severson, W., Xu, X., Kuhn, M., Senutovitch, N., Thokala, M., Ferron, F., Longhi, S., Canard, B. and Jonsson, C.B.
J. Virol. 2005; In Press.
Evaluation of the antineoplastic properties of COX-2 selective inhibitors, celecoxib and rofecoxib in human breast and prostate tumor cell lines: evidence for tissue selectivity involving a COX-2 independent mechanism.
Piazza, G. A., Estlack, L., Quada, J., Agyin, J., Izbicka, E., Tolcher, A., Oyajobi, B., and G. Mundy.
European Journal of Cancer, 2002; 38: S85.
Exisulind and CP248 induce growth inhibition and apoptosis in human esophageal adenocarcinoma and squamous cell carcinoma cells.
Joe, A. K., Liu, H., Xioa, D., Soh, J., Pinto, J. T, Beer, D. G., Piazza, G. A., Thompson, W. J., and I. B. Weinstein.
Journal of Experimental Therapeutics and Oncology 2003; 3:83-94.
Exisulind and docetaxel combination prolongs survival in orthotopic human non-small cell lung cancer rat model.
Bunn, P. A., Chan, D. C., Earle, K., Zhao, T., Helfrich, B., Pallansch, P., Nelson, P., Alila, H., Pamukcu, R., Whitehead, and G. A. Piazza.
Proc. Amer. Ass. Cancer Res. 2001; 43.
Exisulind and related compounds inhibit expression and function of the androgen receptor in human prostate cancer cells.
Lim, J.T., Piazza, G.A., Pamukcu, R., Thompson, W. J., and I. B. Weinstein.
Clinical Cancer Research 2003; 9: 4972-4982.
Exisulind in combination with docetaxel inhibits growth and metastasis of human lung cancer and
prolongs survival in athymic nude rats with orthotopic lung tumors.
Chan, D. C., Earle, K., A., Zhao, T. L., Helfrich, B., Zeng, C., Baron, A., Whitehead, C. M., Piazza, G., Pamukcu, R., Thompson, W., J., Alila, H., Nelson, P. and P. A. Bunn.
Clinical Cancer Research 2002; 8: 904-912.
Exisulind inhibits rat urinary bladder tumorigenesis by cGMP mediated apoptosis. Piazza, G. A., Thompson, W. J., Pamukcu, R., Whitehead, C., Li, L., Fetter, J., Gresh, B., Klein-Szanto, A., Farnell, D., Eto, I., and C. J. Grubbs. Cancer Research 2001; 61: 3961-3968.
Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic model augments docetaxel treatment and contributes to increased survival. Whitehead, C. M., Earle, K., A., Fetter, J., Xu, S., Hartman, T., Chan, D. C., Zhao, T. L., Piazza, G., Klein-Szanto, A. J., Pamukcu, R., Alila, H., P. A. Bunn, and W. J. Thompson. Molecular Cancer Therapeutics 2003; 2: 479-488.
Expressed in and Purified from Escherichia coli and Pichia pastoris.
Pieffer, A., and C. B. Jonsson.
A Comparative Study of the Human T-cell Leukemia Virus Type 2 Integrase Protein Purif. Char. 2002; 25;291-299.
Expression of SNT-1 Phosphotyrosine Binding Domain inhibits Activation of MAP kinase and PI-3-kinase pathways and Antiestrogen-resistant Growth Induced by FGF-1 in Breast Cancer Cells.
Manuvakhova, M., Thottassery, J.V., Susan Hays, Kern, F.G.
Submitted, 2005.
Expression, Purification and Characterization of the Sin Nombre Virus Nucleocapsid Protein in Escherichia coli. Jonsson, C.B., Gallegos, J., Fero, P., Severson, W.E. Xu, X. and C. S. Schmaljohn. Protein Purif. Char. 2001; 23:134-141.
First International Conference on Chemoprevention of Prostate Cancer.
Thompson, I. M., Piazza, G.A. et al.
J. Urol. 2004; 171(2):S3-S4.
Fractionation, structural studies, and immunological characterization of the semi-synthetic Quillaja saponins derivative GPI-0100. Marciani, D.J.; Reynolds, R.C.; Pathak, A.K.; Finley-Woodman, K.; May, R.D. Vaccine 2003; 21(25-26):3961-71.
Glutamate toxicity studies unmask a putative 12-HETE receptor in cortical neurons.
Hampson A.J. and Grimaldi M.
The Journal of Neuroscience 2002; 22(1):257-264.
(Invited Review) Going after Hot Targets in Drug Discovery - Creating a Roadmap for High Throughput Screening of Live Virus Targets that Require Biosafety Level 2 and 3 Containment.
Jonsson, C.B.
Eur. Pharma. Rev. Accepted.
(Invited Review) Going Hot - Creating a Roadmap for High Throughput Screening for Drug Discovery in Biosafety Level 3 Laboratories.
Jonsson, C.B., White, L., Severson, W., Noah, J.
Amer. Biotech. Lab. Accepted.
Growth inhibitory activity of novel marine-derived microtubule binding agents in taxane-sensitive and resistant tumor cell lines.
Piazza, G, Revilla, M., Tanaka, K, Kisa, Y., Hayashi, Y., and M. Palladino.
Proc. Amer. Ass. Cancer Res. 2003.
Hantavirus infection in people inhabiting a highly endemic region of the Gran Chaco territory, Paraguay: association with Trypanosomacruzi infection, epidemiological features and haematological characteristics.
Ferrer J.F., Galligan D., Esteban E., Rey V., Murua A., Gutierrez S., Gonzalez L., Thakuri M., Feldman L., Poiesz B., Jonsson C.
Ann. Trop. Med. Parasitol. 2003; 97:269-280.
High Throughput Primer Walking of cDNA Clones.
Stewart, C., Lum, N., Stephens, R., Rudnick, P., Rasmussen, L., D. Munroe.
Journal of the Association for Laboratory Automation 2003; 8: 64-65.
HMM-176 exhibits marked anticancer activity in an ex-vivo human tumor colony formation assay.
Medina, L, Gomez, L., Cerna, C., and G.A. Piazza.
Proc. Amer. Ass. Cancer Res. 2002; 43: 79.
Homo- and heterodimerization of retinoic acid receptors, RARs and RXRs.
Sani, B.P. and Reddy, L.G.
Expt. Biol., FASEB J. 2002; 16: 743
Homogeneity and Long-Term Stability of Tetracycline-Regulated Gene Expression with Low Basal Activity by using the rtTA2S-M2 Transactivator and Insulator-flanked Reporter Vectors.
Qu, Z., Thottassery, J.V.*, Van Ginkel, S., Manuvakhova, M., Westbrook, L., Roland-Lazenby, C., Hays, S, and Kern F.G.
Gene 2004; 327:61-73
Identification and Characterization of a Novel Allosteric Modulator (SoRI-6238) of the Serotonin Transporter.
Nandi, A.; Dersch, C. M.; Kulshrestha, M.; Ananthan, S.; Rothman, R. B.
Synapse 2004; 53, 176-183.
Identification and Characterization of a unique adenosine kinase from Mycobacterium tuberculosis.
Long, M. C., Escuyer, V. and Parker, W. B.
J. Bacteriol. 2003; 185: 6548-6555.
Identification of a Novel Partial Inhibitor of Dopamine Transporter Among 4-Substituted 2-Phenylquinazolines.
Ananthan, S.; Saini, S. K.; Khare, R.; Clayton, S. D.; Dersch, C. M.; Rothman, R.
Bioorg. Med. Chem. Lett. 2002; 12: 2225-2228.
Identification of novel marine-derived microtubule binding agents and their structure activity relations.
Nicholson, B., Miller, B., Chao, T., Hayashi, Y., Revilla, M, Piazza, G, and M. Palladino.
Proc. Amer. Ass. Cancer Res. 2003.
Identification of Opioid Ligands Possessing Mixed γ Agonist/γ Antagonist Activity among Pyridomorphinans Derived from Naloxone, Oxymorphone, and Hydromorphone.
Ananthan, S.; Khare, N. K.; Saini, S. K.; Seitz, L. E.; Bartlett, J. L.; David, P.; Dersch, C. M.; Porreca, F.; Rothman, R. B.; Bilsky, E. J.
J. Med Chem. 2004; 47, 1400-1412.
Impaired Prostate Tumorigenesis in Egr1-Deficient mice.
Abdulkadir, S.A.; Qu, Z.; Garabedian, E.; Song, S.-K.; Peters, T.J.; Svaren, J.; Carbone, J.M.; Naughton, C.K.; Catalona, W.J.; Ackerman, J.H.; Gordon, J.I.; Humphrey, P.A.; Milbrandt, J.
Nature Medicine 2001; 7(1), 101.
Improved MRI Detection of Prostate Cancer in a Transgenic Mouse Model.
Song, S.-K.; Qu, Z.; Garabedian, E.M.; Gordon, J.I.; Milbrandt, J.; Ackerman, J.H.
Cancer Research 2002; 62, 1555-1558.
In Vitro and In Vivo Evaluation of Aminopeptidase Inhibitors As Antimicrosporidial Therapies.
Millership, J. J.; Didier, E. S.; Okhuysen, P. C.; Maddry, J. A.; Kwong, C. D.; Chen, X.; Snowden, K. F.
J. Eukaryot. Microbiol. 2001; Suppl., 95S-98S.
In Vivo Pharmacological Characterization of SoRI 9409, a Nonpeptidic Opioid γ -Agonist/γ -Antagonist That Produces Limited Antinociceptive Tolerance and Attenuates Morphine Physical Dependence.
Wells, J. L.; Bartlett, J. L.; Ananthan, S.; Bilsky, E. J.
J. Pharmacol. Exp. Ther. 2001; 297, 597-605.
Increase survival and reduced tumor burden from exisulind and docetaxel combination in an orthotopic human NSCLC rat model.
Chan, D., Earle, K., Alila., H., Piazza, G. A., Pamukcu, R., Whitehead, C. and P. Bunn.
Proc. Amer. Ass. Cancer Res. 2001; 43.
Inhibition of papilloma formation by analogues of 7,8-dihydroretinoic acid.
Shealy, Y.F., Riordan, J.M., Frye, J.L., Herren, L.-S., Sani, B.P., Hill, D.L.
J. Med. Chem. 2003; 46: 1931-1939.
Interactions of the human T-cell leukemia virus type-II integrase with the conserved CA in the retroviral long terminal repeat end.;
Wang, T., Pieffer, A., and C. B. Jonsson.
J. Biol. Chem. 2001; 276:14710-15717.
Land Cover Associated with Hantavirus Presence in Paraguay.
Goodin, D.G., Kocj, D.E., Owen, R.D., Chu, Y.K., Hutchinson, S., and Jonsson, C.B.
Global Ecology and Biogeography. 2006; 15:519-527.
LC/MS/MS-based proteomic analysis of the membrane proteins of human prostate carcinoma LNCaP cells.
Jia, L, Wong, H., Cerna, C., and G. Piazza.
Proc. Amer. Ass. Cancer Res. 2002; 43:34.
Long intracellular retention of 4'-thio-arabinofuranosylcytosine 5'-triphosphate as a critical factor for the anti-solid tumor activity of 4'-thio-arabinofuranosylcytosine.
Someya H, Waud WR, Parker WB.
Cancer Chemother. Pharmacol. 2006; 57: 772-780.
Lytic peptide Phor21-BCG(ala) II: Selective cytotoxicity and its effects on membrane integrity as measured by permeability to mannitol.
Piazza, G. A., Jones, A., Noker, P., Hansel, W., Leuschner, and L. Jia.
Proc. Amer. Ass. Cancer Res. 2005.
Mathematical Models for Hantavirus Infection in Rodents.
Allen, L.J.S McCormack, R.K. and Jonsson, C.B.
Bull. Math. Biol. 2006; 68: 511-524.
Mdr1b Facilitates p53-Mediated Cell Death and p53 is Required for Mdr1b Upregulation in vivo.
Lecureur, V., Thottassery, J. V. *, Zambetti, G. P., Sun, D., Schuetz, E.G. and Schuetz, J. D.
Oncogene 2001; 20:303-313.
Mechanism of maturase-promoted group II intron splicing.
Matsuura M., Noah J.W. (co-first author), and Lambowitz A.M.
EMBO J. 2001; 20(24) 7259-70.
Metabolism of 2-Methyladenosine in Mycobacterium tuberculosis.
Parker, W. B.; Barrow, E. W.; Allan, P. W.; Shaddix, S. C.; Long, M. C.; Barrow, W. W.; Bansal, N.; Maddry, J. A.
Tuberculosis 2004; 84, 327-336.
Mitochondria in signaling microdomains: regulation of calcium wave initiation and signal transduction in oligodendrocyte precursor cells.
Haak L.L., Grimaldi M., Smaili S., Heng P., J.T. Russell.
J. Neurochemistry 2002; 80(3):405-415.
Mobilization of calcium from intracellular stores, potentiation of neurotransmitter induced calcium transients and capacitative calcium entry by 4-aminopyridine.
Grimaldi M. et al.
The Journal of Neuroscience 2001; 21(9):3135-3143.
Monoclonal antibodies specific to the RNA binding domain of the Hantaan virus nucleocapsid protein inhibit encapsidation and virus replication in vitro.
Jonsson, C.B., McDowell, M., Chu, Y., Severson, W.E., Fero, P.J. Chung, D., Ali., G., Plane, S. and M.C. Guttieri.
manuscript in preparation 2005.
Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells.
Shewach DS, Murphy PJ, Robinson BW, Vuletich J, Boucher PD, Blobaum AL, Serbe L, Secrist JA III, and Parker WB.
Human Gene Therapy 2002; 13: 543-551.
Native TRPC activation mediates novel calcium oscillation but not capacitative calcium entry in astrocytes.
Grimaldi M. et al.
he Journal of Neuroscience 2003; 23(11):4737-4745.
Naturally occurring substitutions of the human T-cell leukemia virus type 1 3' LTR influence strand-transfer reaction.
Leclercq I., Mortreux F., Rabaaoui S., Jonsson C.B., and E. Wattel.
J. Virol. Methods. 2003; 109:105-17.
New Mycobacterium avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors.
Suling, W.J., Seitz, L.E., Reynolds, R.C., Barrow, W.W.
Antimicrob. Agents Chemother. 2005; 49:4801-4803.
Novel Ligands for the Opioid Receptors: Synthesis and Structure - Activity Relationships among 5γ
-Aryl and 5γ -Heteroaryl 17-Cyclopropylmethyl-4,5γ -epoxy-pyrido[2γ ,3γ :6,7]morphinans.
Ananthan, S.; Khare, N. K.; Saini, S. K.; Davis, P.; Dersch, C. M.; Porreca, F.; Rothman, R. B.
Bioorg. Med. Chem. 2003; 11, 4143-4154.
NSAIDs and cyclooxygenase-2 inhibitors for prostate cancer chemoprevention.
Basler, J. W. and Piazza, G.A.
J. Urol. 2004; 171(2):S59-S63.
On the Development of a Database to Monitor and Model the Impact of Rapid Anthropogenic Land Cover Changes on the Hantavirus Ecology in Paraguay.
C.B. Jonsson, R.D. Owen, P.H. Tu, E. Pontelli, T.C. Son.
In preparation.
Phosphodiesterase 5 overexpression in human non-small cell lung tumors compared to normal bronchial epithelium.
Piazza, G. A., Klein-Szanto, Xu, S., Pamukcu, R. and W. J. Thompson.
Proc. Amer. Ass. Cancer Res. 2001; 43.
Phosphodiesterase 5 overexpression in human pancreatic cancer.
Piazza, G. A., Klein-Szanto, Xu, S., Pamukcu, R. and W. J. Thompson.
Gastroenterology 2001.
Phosphorylation of 4'-thio-arabinofuranosylcytosine and its analogs by human deoxycytidine kinase.
Someya H, Shaddix SC, Tiwari KN, Secrist JA III, and Parker WB.
J. Pharmacol. Exp. Ther. 2003; 304: 1314-1322.
Phylogenetic and Geographical Relationships of Hantavirus Strains in Eastern and Western Paraguay.
Chu, Y.K. Milligan, B., Owen, R.D., Goodin, D.G. and C. B. Jonsson.
Amer. J. Trop. Med. 2006; In press.
Pivanex, a histone deacetylase inhibitor, is synergistic with chemotherapy inhibiting the growth of human non-small cell lung cancer lines.
Sreedharan, S., Revilla, M., Estlack, L., Wirtz, U., Valone, F., and G. A., Piazza.
Proc. Amer. Ass. Cancer Res. 2003.
Pivanex, a histone deacetylase inhibitor, is synergistic with the proteosome inhibitor Velcade in inhibiting the growth of human non-small cell lung cancer cells. Wirtz, U., Jones, A. Sreedharan, S., Bhatnagar, A., and G. A. Piazza. Proc. Amer. Ass. Cancer Res. 2005.
Polymerization of C-terminally truncated Mycobacterium tuberculosis FtsZ is unlikely to be physiologically relevant.
Borhani, D.W.; White, E.L.
Microbiol. 2004; 150: 2903-3906.
(Invited Review) Potential Importance of Error Catastrophe to the Development of Antiviral Strategies for Hantaviruses.
Jonsson, C.B., Milligan, B., Arterburn, J.A.
Virus Res. 2005; 107:195-205.
Preclinical and clinical studies of docetaxel and exisulind in the treatment of human lung cancer.
Bunn, P. A., Chan, D. C., Earle, K., A., Zhao, T. L., Helfrich, B., Kelly, K., Piazza, G., Whitehead, C. M., Pamukcu, R., Thompson, W., J., and Alila, H.
Seminars in Oncology 2002; 29: 87-94.
Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models.
Lenaerts, A.J.; Gruppo, V.; Marietta, K.S.; Johnson, C.M.; Driscoll, D.K.; Tompkins, N.M.; Rose, J.D.; Reynolds, R.C.; Orme, I.M.
Antimicrobial Agents and Chemotherapy 2005; 49(6), 2294-301.
Prevalence of antibodies to Sin Nombre virus in humans living in rural areas of southern New Mexico and western Texas. Gonzalez, L.M., Lindsey, A.E., Hjelle, B, Dominguez, D., Brown, J. and C.B. Jonsson. Virus Res. 2001; 74:177-179.
Primary Breast Fibroblasts Modulate Epithelial Cell Proliferation in Three-Dimensional In Vitro Co-Culture. Sadlonova, A., Johnson, M. R., Bowe, D. B., Moore, C. S., Gault, S.R., Page, G. P., Thottassery, J. V., Welch D.R. and Frost, A.R. Breast Cancer Res. 2005; 7: R46-R49.
Pro-apoptotic actions of exisulind in SW480 colon tumor cells involved B-catenin down regulation.
Li, H., Liu, L., David, M., Whitehead, C., Chen, M., Fetter, J., Piazza, G., W. J. Thompson.
Proc. Amer. Ass. Cancer Res. 2001; 43.
Prolonged MEK-ERK 1/2 Activation During FGF-1 or Heregulin γ 1 Induced Antiestrogen-Resistant Growth of Breast Cancer Cells is Resistant to MEK Blockers. Thottassery, J.V., Yanjie Sun, Louise Westbrook, Sarah Rentz, Marina Manuvakhova, Zhican Qu, Shanti Samuel, Ramanda Upshaw, Amanda Poe, and Kern, F.G. Cancer Research 2004; 64: 4637-4647.
Purification and characterization of Hantaan virus 246 kDa RNA dependent RNA polymerase (RdRp).
Leon, L.R, Severson, W., Thokala, M., Gallegos, J.G. and C.B. Jonsson.
FASEB 2002; v.16, no.4, pt.1, p.A165-A165.
Purification and characterization of the Sin Nombre virus nucleocapsid protein expressed in Escherichia coli.
Jonsson, C.B., Gallegos, J., Fero, P., Severson, W.E., Xu, X. and C.S.Schmaljohn.
Protein Purification and Expression. 2001; 23:134-141.
Purine nucleoside antimetabolites in development for the treatment of cancer.
Parker WB, Secrist JA III, and Waud WR.
Curr. Opin. Investig. Drugs 2004; 5: 592-596.
Quillaja saponin adjuvants: derivatives formed under sub-optimal conditions.
Marciani, D.; Pathak, A.; Reynolds R.C.
Vaccine 2002; Sep 10;20(27-28):3237.
Rapid, high-throughput purification of HIV-1 integrase using microplate technology.
Wang, T., S. John, S. Archuleta, and C. B. Jonsson.
Protein Purif. Char. 2004; 33:232-7.
Recent advances in mycobacterial arabinogalactan biosynthesis in the post-genomics era.
Kremer, L; Dover, L.G.; Gurcha, S.S.; Pathak, A.K.; Reynolds, R.C.; Besra, G.S.
Carbohydrate Bioengineering. Royal Society of Chemistry 2002; 178-185.
(Invited Review) Replication of Hantaviruses.
Jonsson, C. B. and C.S. Schmaljohn.
In Current Topics in Microbiology and Immunology, Schmaljohn and Nichol, Eds. Berlin, Springer-Verlag. 2001; pp 15 -32.
Response in the 16S rRNA during formation of P/P- and P/E-site tRNAPhe-mRNA complexes in the Escherichia coli 70S ribosome.
Noah, J.W., Shapkina, T.S., Nanda, K., Huggins, W., and Wollenzien, P.
Biochemistry 2003; 42(49) 14386-96.
Revealing Domain Structure through Linker-Scanning Analysis of the MuLV RNaseH, MuLV and HIV-1 Integrase Proteins.
Puglia, J., Wang, T., Smith-Synder, C., Cote, M., Pelletier, J., John, S., Jonsson, C.B., and Roth, M.J.
J. Virol. 2006; Accepted.
Ribavirin causes error catastrophe during Hantaan virus replication.
Severson, W.E., Schmaljohn, C. S., Javadian, M.A. and C.B. Jonsson.
J. Virol. 2003; 77:481-488
Search for new drugs for treatment of tuberculosis.
Secrist, J., S. Ananthan, C. Kwong, J. Maddry, R. Reynolds, A. Poffenberger, M. Michael, L. Miller, J. Krahenbuhl, L. Adams, A. Biswas, S. Franzblau, D. Rouse, D. Winfield, J. Brooks.
Antimicrobial Agents and Chemotherapy 2001; 45(7): 1943-1946.
Search for new drugs for treatment of tuberculosis: Tuberculosis Drug Screening Program.
Orme, I.: Secrist, J.; Ananthan, S.; Kwong, C.; Maddry, J.; Reynolds, R.; Poffenberger, A.; Michael, M.; Miller, L.; Krahenbuhl, J.; Adams, L.; Biswas, A.; Franzblau, S.; Rouse, D.; Winfield, D.
Antimicrob Agents Chemother. 2001; 45(7):1943-6.
Sequence validation and analysis for microarray production.
Stephens, R., Stewart, C., Medjahed, D., Rasmussen, L., Gangi, L., Mayer, S., Owens, G., Burgess, T., Burt, S., and D. J. Munroe.
Manuscript in preparation 2004.
SERCA inhibitors identify a novel calcium pool in the central nervous system.
Watson W.D., Facchina S.L., Grimaldi M., Verma A.
Journal of Neurochemistry 2003; 87:30-43.
SJ-3366, A Unique and Highly Potent Nonnucleoside Reverse Transcriptase Inhibitor of HIV-1 That also Inhibits HIV-2.
Buckheit, R.W., Jr.; Watson, K.; Fliaksa-Boltz, V.; Russell, J.; Loftus, T.L.; Osterling, M.C.; Turpin, J.A.; Pallansch, L.A.; White, E.L.; Lee, J-W.; Lee, S-H.; Oh, J-W.; Kwon, H-S.; Chumg, S-G.; Cho, E.H.
Antimicrob.Agents Chemother. 2001; 45, 393-400.
SoRI-9409, a Non-peptide Opioid Mu Receptor Agonist/Delta Receptor Antagonist, Fails to Stimulate [35S]GTP-γ -S Binding at Cloned Opioid Receptors.
Xu, H.; Lu, Y-F.; Rice, K. C.; Ananthan, S.; Rothman, R. B.
Brain Research Bulletin 2001; 55, 507-511.
Spatio-temporal Distribution of Old World and New World Hantavirus Nucleocapsid Proteins.
S.J. Plane, H. Ramanathan, Y.K. Chu, G.D. Ali, E. Sztul, and C. B. Jonsson.
Submitted.
Special Volume on Retinoid Receptors.
Sani, B. P. Guest Editor
Cellular Mole. Life Sci. (formerly Experientia) In preparation.
Specific Localization of the annexin II heterotetramer in brain lipid raft fractions and its changes in spatial learning.
Zhao W., Weissman D.M., and Grimaldi M.
J. Neurochemsitry 2004; 90:609-20.
SRI-286, a Thiosemicarbazole, in Combination with Mefloquine and Moxifloxacin for Treatment of Murine Mycobacterium avium Complex Disease.
Bermudez, L.E.; Kolonoski, P.; Seitz, L.E.; Petrofsky, M.; Reynolds, R.; Wu, M.; Young, L.S.
Antimicrob. Agents Chemother. 2004; 48, 3556-3558.
Structure of Mycobacterium tuberculosis FtsZ Reveals Unexpected, G Protein-Like Conformational Switches.
Leung, A.K.W.; White, E.L.; Ross, L.J.; Reynolds, R.C.; DeVito, J.A.; Borhani, D.W.
Journal of Molecular Biology 2004; 342, 953-970.
Studies of the Biogenic Amine Transporters. VIII: Identification of a Novel Partial Inhibitor of Dopamine Uptake and Dopamine Transporter Binding. Rothman, R. B.; Dersch, C. M.; Carroll, F. I.; Ananthan, S. Synapse 2002; 43, 268-274.
Studies on α (1—>5) Linked Octyl Arabinofuranosyl Disaccharides for Mycobacterial Arabinosyl Transferase Activity.
Pathak, A. K.; Pathak, V.; Maddry, J. A.; Suling, W. J.; Gurcha, S. S.; Besra, G. S.; Reynolds, R. C.
Bioorg. Med. Chem. 2001; 9, 3145-3151.
Studies on (β,1—>5) and (β,1—>6) linked octyl galf disaccharides as substrates for mycobacterial galactosyltransferase activity.
Pathak, A.K., Pathak, V., Seitz, L., Maddry, J.A., Gurcha, S.S., Flaherty, C., Besra, G.S., Suling, W.J., Reynolds, R.C.
Bioorg. Med. Chem. 2001; 9:3129-3143.
Studies on n-octyl-5-(α-D-arabinofuranosyl)-β-D-galactofuranosides for mycobacterial glycosyltransferase activity.
Pathak, A.K, Pathak, V., Suling, W.J., Gurcha, S.S., Morehouse, C.B., Besra, G.S., Maddry, J.A., Reynolds, R.C.
Bioorg. Med. Chem. 2002; 10:923-928.
Studies on nuclear retinoic acid receptor dimerization and dimer DNA interactions.
Sani, B. P., Reddy, L.G. and Venepally, P.
Current Trends Biochem. Res. In press.
Sulindac inhibits nuclear translocation and causes proteosome- and caspase-dependent degradation of B-catenin.
Rice, P., Kelloff, J., Kuwada, S., Driggers, L., Schleman, S., Piazza, G., and D. J. Ahnen.
Proc. Amer. Ass. Cancer Res. 2002; 43: 67.
Sulindac metabolites induce caspase- and proteasome-dependent degradation of á-catenin protein in human colon cancer cells.
Rice, P.L.; Kelloff, J.; Sullivan, H.; Driggers, L.J.; Beard, K.S.; Kuwanda, S.; Piazza, G.; and D. J.
Ahnen Molecular Cancer Therapeutics 2003; 2: 885-892.
Synthesis and antimycobacterial activity of pyrazine and quinoxaline derivatives.
Seitz, L.E., Suling, W.J., Reynolds, R.C.
J. Med. Chem. 2002; 45:5604-5606.
Synthesis and Antitumor Evaluation of the Aminopterin Analogue with the Bicyclo[2.2.2]octane Ring in Place of the Benzene Ring.
Reynolds, R.C.; Johnson, C.A.; Piper, J.R.; Sirotnak, F.M.
European Journal of Medicinal Chemistry 2001; 36, 237-42.
Synthesis and biological evaluation of trehalose analogs as potential inhibitors of mycobacterial cell wall biosynthesis.
Rose, J.D., Maddry, J.A., Comber, R.N., Suling, W.J., Wilson, L.N., Reynolds, R.C.
Carbohydrate Res. 2002; 337:105-120.
Synthesis and preliminary in vitro evaluation of antimycobacterial activity of new pyrrolo[1,2-a] quinoxaline-carboxylic acid hydrazide derivatives.
Guillon, J.; Reynolds, R.C.; Leger, J.-M.; Guie, M.-A.; Massip, S.; Dallemagne, P.; Jarry, C.
Journal of Enzyme Inhibition and Medicinal Chemistry 2004; 19(6): 489-495.
Synthesis and structure activity relationship of 5-substituted-4'-thio-β-D-arabinofuranosylcytosines.
Tiwari KN, Shortnacy-Fowler AT, Cappellacci L, Waud WR, Parker WB, Montgomery JA, Secrist JA III.
Nucleosides, Nucleotides, & Nucleic Acids 2001; 19: 2005-2017
Synthesis of a Fluorescent Arabinofuranosyl Disaccharide: A Probe for Arabinosyltransferase Activity in Mycobacterium tuberculosis.
Pathak, A. K.; Pathak, V.; Bansal, N.; Maddry, J. A.; Reynolds, R. C.
Tetrahedron Lett. 2001; 42, 979-982.
Synthesis of an arabinofuranosyl disaccharide photoaffinity probe for arabinosyltransferase activity in Mycobacterium tuberculosis.
Pathak, A.K.; Pathak, V; Gurcha S.S.; Besra, G.S.; Reynolds, R.C.
Bioorg. Med. Chem. Lett. 2002; 12(19):2749-2752.
Synthesis of Disaccharides Related to the Mycobacterial Arabinogalactan.
Pathak, A.K.; Pathak, V.; Khare, N.K.; Maddry, J.A.; Reynolds, R.C.
Carbohydrate Letters 2001; 4(2), 117-22.
Synthesis of mannopyranose disaccharides as photoaffinity probes for mannosyltransferases in Mycobacterium tuberculosis.
Pathak, A.K.; Pathak, V.; Riordan, J.M.; Gurcha, S.S.; Besra, G.S.; Reynolds, R.C.
Carbohydr. Res. 2004; 339, 683-691.
Synthesis of novel 5-aryl-2-thio-1,3,4-oxadiazoles and the study of their structure-anti-mycobacterial activities.
Macaev, F.; Rusu, G.; Pogrebnoi, S.; Gudima, A.; Stingaci, E.; Vlad, L.; Shvets, N.; Kandemirli, F.; Dimoglo, A.; Reynolds, R.C.
Bioorganic and Medicinal Chemistry 2005; 13, 4842-50.
Synthesis, Opioid Receptor Binding, and Functional Activity of 5γ -Substituted 17-Cyclopropylmethylpyrido[2γ,3γ :6,7]morphinans.
Ananthan, S.; Kezar III, H. S.; Saini, S. K.; Khare, N. K.; Davis, P.; Dersch, C. M.; Porreca, F.; Rothman, R. B.
Bioorg. Med. Chem. Lett. 2003; 13, 529-532.
The complex ecology of hantavirus in Paraguay.
Chu, Y.K., Gonzalez, L., Owen, R., and C.B. Jonsson.
Amer. J. Trop. Med. Hyg. 2003; 69:263-8.
The Emb proteins of mycobacteria direct atabinosylation of lipoarabinomannan and arabinogalactan via an N-terminal recognition region and a C-terminal synthetic region.
Zhang,N., Torrelles, J.B., McNeil, M. R., Escuyer, V.E., Khoo, KH., Brennan P. J. and Chatterjee, D.
Mol. Microbiol. 2003l 50: 69-76.
The Metabolism of 2-Methyladenosine in Mycobacterium smegmatis.
Chen, C.-K.; Barrow, E. W.; Allan, P. W.; Bansal, N.; Maddry, J. A.; Suling, W. J.; Barrow, W. W.; Parker, W. B.
Microbiology 2002; 148, 289-295.
The neuropeptide PACAP activates a unique combinatorial signal transduction pathway targeting the VIP gene.
Hamelink C., Hyeon-Woo L., Hahm S., Grimaldi M., Eiden L.
The Journal of Neuroscience 2002; 22(13): 5310-5320
The RNA binding domain of the Hantaan virus N protein maps to a central, conserved region.
Xu, X., Severson, W.E. and C.B. Jonsson.
J. Virol. 2002; 76:3301-3308.
The role of the embA, B gene products in the biosynthesis of the terminal hexaarabinofuranosyl motif of Mycobacterium smegmatis arabinogalactan.
Escuyer, V.E., Lety, M.A., Torrelles, J.B., Khoo, K.H., Tang, J.B., Rithner, C.D., Frehel, C., McNeil M. R., Brennan P.J. and Chatterjee D.
J. Biol. Chem. 2001; 276: 48854-48862.
The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.
Waddell, S.J.; Stabler, R.A.; Laing, K.; Kremer, L.; Reynolds, R.C.; Besra, G.S.
Tuberculosis (Edinb). 2004; 84(3-4), 263-74.
Therapeutic Strategies for Human Microsporidia Infections.
Didier, E.S.; Maddry, J. A.; Brindley, P. J.; Stovall, M. E.; Didier, P. J.
Expert Rev Anti-Infect Ther 2005; 3(3), 419-434.
Thiosemicarbazole (Thiacetazone-Like) Compound with Activity against Mycobacterium avium in Mice. Bermudez, L.E.; Reynolds, R.C.; Kolonoski, P.; Aralar, P.; Inderlied, C.B.; Young, L.S.
Antimicrob. Agents. Chemother. 2003; 47(8):2685-2687.
Transcription of MyoD and myogenin in the non-contractile electrogenic cells of the weakly electric fish S. macrurus.
Kim J.A, Jonsson C.B., Calderone T., and GA Unguez.
Develop Genes Evol. 2004; 214:380-392
Translocation of protein kinase C-áII from cytosol to membrane-associated Receptor for Activated C Kinase 1 in type I astrocytes requires intact actin cytoskeleton. Pascale A., Alkon D.L, and Grimaldi M.
Glia 2004; 42(6):169-182
Unexpected and striking synergism between gemcitabine and sulindac sulfide to inhibit the growth of human pancreatic tumor cell lines.
Piazza, G. A., Jones, A. and P. R. Holt.
Proc. Amer. Ass. Cancer Res. (Late breaking abstract session). 2004.
Utilizing a new tool for drug discovery: Building a better toolbox for research by increasing the availability of molecular probes.
Piazza, G.A.
Genetic Engineering News 2005; 25: 44-46. Publications (Abstracts).
VEGFA165 Promotes Tamoxifen Resistance Metastatic Colonization, and Desmoplasia in ER Positive Breast Cancer Xenografts: A New Model for VEGF Functions Beyond Angiogenesis.
Qu, Z., Van Ginkel, S., Roy-Mittal, A., Nasrin, M., Thottassery, J.V., Westbrook, L.W., Carey, D., Li, R., Grizzle, W.E., Kern, F.G.
In preparation.
Yersinia pseudotuberculosis harbors a type IV pilus gene cluster that contributes to pathogenicity.
Collyn, F., Lety, M. A., Nair, S., Escuyer, V., Ben Younes, A., Simonet, M. and Marceau, M.
Infect. Immun. 2002; 70: 6196-6205.
Abstracts
Measurement of Fluorescent FtsZ from Mycobacterium tuberculosis in a High-Throughput Assay.
Madison-Antenucci, S.; Ross, L.J.; White. E.L.; Fletcher, T.M.III.
Gordon Research Conference on Tuberculosis Drug Development, Oxford, UK. August 31 - September 5, 2003.
A High Throughput Screen for the Mycobacterium Tuberculosis Enoyl Acyl Carrier Protein Reductase.
White, E.L.; Gill, R.; Drummond, T., Fletcher, T.M.III.
InhA. Society for Biomolecular Screening 9th Annual Conference, Portland, Oregon. September 22-25, 2003.
Measurement of Fluorescent FtsZ from Mycobacterium tuberculosis in a High-Throughput Assay.
Madison-Antenucci, S.; Ross, L.J.; White. E.L.; Fletcher, T.M.III.
Society for Biomolecular Screening 9th Annual Conference, Portland, Oregon. September 22-25, 2003.
An Automated High Throughput Screen for Dihydrofolate Reductase Using Catalytic Reduction of MTS to Identify Inhibitors of Mycobacterium Tuberculosis.
Gill, R.; Drummond, T.; Escuyer, V.; Ingrum, M.; Ross, L.J.; White, E.L.; Suiling, W.J.; Fletcher, T.M.III.
Society for Biomolecular Screening 9th Annual Conference, Portland, Oregon. September 22-25, 2003.
A High Throughput Screening Assay for Isocitrate Lyase Inhibitors of Mycobacterium tuberculosis.
Sneed, Blossom; van-Ginkel, Sabrina; Gill, Rachel; Ross, Larry; Ingrum Sosa, Melinda; Cooley, Sara; Pate, Anthony; Manouvakhova, Anna; Lampl, Mindy; Barnett, David; White, E. Lucile; Fletcher III, Thomas M.; Sacchettini, James C.
10th Annual Society for Biomolecular Screening Conference, Orlando, FL. Sept.11-15, 2004.
High Throughput Screening Assay for Inhibitors of Mycobacterium tuberculosis Enoyl ACP Reductase (InhA).
Gill, Rachel; Ross, Larry; Ingrum Sosa, Melinda; Cooley, Sara; Pate, Anthony; Manouvakova, Anna; Lampl, Mindy; Barnett, David; White, E. Lucile; Sacchettini, James C.; Fletcher III, Thomas M.
10th Annual Society for Biomolecular Screening Conference, Orlando, FL. Sept.11-15, 2004.
High Throughput Screening Assay for Pantothenate Synthetase Inhibitors of Mycobacterium tuberculosis.
Sneed, Blossom; Ross, Larry; Ingrum Sosa, Melinda, Cooley, Sara; Pate, Anthony; Manouvakhova; Barnett, David; White, E. Lucile; Fletcher III, Thomas M.; Wang, ShuiShu; Eisenberg, David; Goulding, Celia W.
10th Annual Society for Biomolecular Screening Conference, Orlando, FL. Sept.11-15, 2004.
High Throughput Screening Assay for Inhibitors of Plasmodium falciparum Enoyl ACP Reductase (PfENR).
Gill, Rachel; Rasmussen, Lynn; Ross, Larry; Ingrum Sosa, Melinda; Cooley, Sara; Pate, Anthony; Manouvakova, Anna; Barnett, David; White, E. Lucile; Kuo, Mack; Sacchettini, James C.; Fletcher III, Thomas M.
10th Annual Society for Biomolecular Screening Conference, Orlando, FL. Sept.11-15, 2004.
Development, Validation and Optimization of a Luminescence-Based High Throughput Screen for Inhibitors of Severe Acute Respiratory Syndrome Coronavirus.
Fletcher III, Thomas M.; Southworth, Kristen; Kushner, Nicole; Cooley, Sara; Sneed, Blossom; Lampl, Mindy; Ingrum, Melinda; Pate, Anthony; Manouvakova, Anna; Barnett, David; Gagliano, Charles; Taggart, Barbara; Rowe, Thomas; Hogan, Jeff; Voss, Thomas G. White, E. Lucile; Buckwold, Victor.
10th Annual Society for Biomolecular Screening Conference, Orlando, FL. Sept.11-15, 2004.
Development, Validation and Screening for Inhibitors of Severe Acute Respiratory Syndrome Coronovirus in a Luminescence-Based High Throughput Screen.
White E., Lucile; Shindo, Nice; Sosa, Melinda I.; Rowe, Thomas; Hogan, Jeff, Kushner, Nicole; Taggart, Barbara; McDowell, Michael; Todd, Jenny; Cooley, Sara, Manouvakova, Anna; Fletcher III, Thomas M.; Buckwold, Victor E.; Jonsson, Colleen B.
11th Annual Society for Bimolecular Screening Conference, Geneva, Switzerland. September 11-15, 2005.
Development and Implementation of a HTS Assay for Inducers of the Excitatory Amino Acid Transporter-2 (EAAT-2).
Piazza, Gary A.; White, E. Lucile; Sneed, Blossom Y.; Kushner, Nicole; Harwell, Joyce E.; Jones, Angela Y.; Southworth, Kristen; Rasmussen, Lynn; Cooley, Sara; Sosa, Melinda I.; Manouvakova Ana; Fletcher II, Thomas M.; Maddry, Joseph A.; Maddry, Ananthan, Subramaniam; Heemskerk, Jill; Rothstein, Jeffrey D.
11th Annual Society for Bimolecular Screening Conference, Geneva, Switzerland. September 11-15, 2005.
A Fluorescence Polarization High Throughput Screening Assay for Activators of Insulin Degrading Enzyme.
Reddy, Lakshmi; Southworth, Kristen; Greenwood, John; Ross, Larry; Cooley, Sara; Ingrum Sosa, Melinda; Manouvakhova, Anna; McGhee, Melanie; Feng, Shuang; Maddox, Clinton; Barnett, David; Rasmussen, Lynn; White, E. Lucile; Maddry, Joseph A.; Heemskerk, Jill; Leissring, Malcolm.
12th Annual Society for Bimolecular Sciences Conference, Seattle, Washington. September 18-21, 2006.
A High Throughput Screening Assay for Malate Synthase Inhibitors of Mycobacterium tuberculosis.
Cooley, Sara; Southworth, Kristen; Ross, Larry; Reddy, Lakshmi; Gray, Rita; Ingrum Sosa, Melinda; Manouvakhova, Anna; Maddox Clinton; Barnett, David; Rasmussen, Lynn; White, E. Lucile; Fletcher III , Thomas M.; Goldman, Robert C.; Sacchettini, James C.
12th Annual Society for Bimolecular Sciences Conference, Seattle, Washington. September 18-21, 2006.
A Colorimetric High Throughput Drug Screening Assay for Friedreich Ataxia.
Kushner, Nicole; Cooley, Sara; Ingrum Sosa, Melinda; Manouvakhova, Anna; Rasmussen, White, E. Lucile; Maddry, Joe; Heemskerk, Jill; Wilson, Robert B.
12th Annual Society for Bimolecular Sciences Conference, Seattle, Washington. September 18-21, 2006.
A Novel High Potency Inhibitor of the Pantothenate Pathway in Bacteria.
White, E. Lucile; Southworth, Krissy; Sneed, Blossom; Ross, Larry; Reddy, Lakshmi; Ingrum Sosa, Melinda; Cooley, Sara Cooley; Manouvakhova, Anna; Rasmussen, Lynn; Barnett, David; Hobrath, Judith; Ananthan, Subramaniam; Maddry, Joseph; Poffenberger, Adrian; Piazza, Gary; Eisenberg, David; Goulding, Celia W.
12th Annual Society for Bimolecular Sciences Conference, Seattle, Washington. September 18-21, 2006.
